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Figuring out the mechanism of action (MOA) of novel or naturally happening compounds mainly depends on assays personalized for unique target proteins. In this article we explore an alternative approach based upon sample matching response profiles attained making use of cultured neuronal networks. Conolidine and cannabidiol are plant-derivatives wit
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Management of Persistent pain carries on to represent a region of great unmet biomedical need. Although opioid analgesics are usually embraced as the mainstay of pharmaceutical interventions Within this area, they put up with substantial liabilities which include dependancy and tolerance, together with melancholy of breathing, nausea and Long-term
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